- Bee venom is a clean and clear aromatic liquid with a bitter taste, which dries quickly at room temperature. After evaporation, 30%–40% of it remains as crystal (refer to the picture).
- Dried bee venom is thermostable, so it does not lose its characteristics even when heated at 100°C, but it can be destroyed by oxidizing materials.
Table 1. Pharmacological Actions and Substances of Bee Venom
Substance
Pharmacological Action
Dry Weight (%)
Molecular Weight (kD)
Melittin
Cell-dissolving action
40-50
2.8
Apamin
Neuralgia relief, pain relief, anti-inflammatory effect, immunization, and neurotoxic effect
2-3
2.02
MCD-Peptide 401
Anti-inflammatory effect
2-3
2.6
Adolapin
Anti-inflammatory effect, pain relief, and fever alleviation effect
0.5-1
11.5
Protease inhibitor
Inhibition of dissolving protein and ester, and anti-inflammatory action
0.1-0.8
9.0
Secapine
Hypothermia relief
0.5-2
2
Procamine A, B
Radiation protection
1-2
0.4
Hyaluronidase
Tissue breakdown and antigenic substance
1
38
Phospholipase A2
Cell tissue breakdown and hemolytic and catalytic actions
10-13
19
Histamine
Blood pressure reduction, intestinal contraction, and enhanced stomach acid secretion
0.5-2
0.12
Dopamine
Neurotransmitter
0.2-1
0.15
Necessity of bee venom
- Made from pure natural materials
- Strong antibacterial, anti-inflammatory, and immune-enhancing effects
- Low risk of adverse effects and residues
- Used for treating various diseases in oriental medicine for a long time
